Sometimes you just want to get away and explore a totally new city. And for that, we’ve got you covered. It just so happens Thrillist has massive, comprehensive travel guides to great American cities like NOLA, San Diego, Miami, Austin, and Vegas(spoiler: all on this list). From bars and restaurants, iconic foods, and live tunes, to museums, outdoor activities, and where to stay (not to mention beaches, parks, and ease of getting around), we know what it takes to have a damn good time in a new place.
Which is why we tapped our crack staff of writers and editors across the country to whittle down 300-plus American cities (with populations over 90k) to the absolute 25 best for spending three days. It wasn’t easy, but, in the end, we came up with a bucket list we think stands up to the test. And one we think you’ll want to start working your way through right away.